1.Research Interests

Synthetic Methodology, Green Organic Synthesis

2.Paper

[1]Zhou, R.;Goh Y. Y.; Liu, H.; Tao, H.; Li, L.; Wu, J.* “Visible-Light-Mediated Metal-Free Hydrosilylation of Alkenes through Selective Hydrogen Atom Transfer for Si-H Activation” Angew. Chem. Int. Ed. 2017, 56, 16621-16625. (Featured in Synfacts 2018, 14, 0198) (IF: 12.257)

[2]Zhou, R.; Liu, H.; Tao, H.; Yu, X.; Wu, J.* “Metal-free direct alkylation of unfunctionalized allylic/benzylic sp3 C-H bonds via photoredox induced radical cation deprotonation” Chem. Sci. 2017, 8, 4654-4659. (Featured in Synfacts 2017, 13, 0819) (IF: 9.556)

[3]Zhou, R.; Li, J.; Cheo, H. W.; Chua, R.; Zhan, G.; Hou, Z.; Wu, J.* "Visible-Light-Mediated Deuteration of Silanes with Deuterium Oxide" Chem. Sci.2019, 10, 7340-7344. (Cover Article) (IF: 9.556)

[4]Liu, R.; Liu, J; Cao, J.; Li, R.; Zhou, R.*; Qiao, Y.; W.-C. Gao* "Chemo- and Diastereoselective Synthesis of Pyrrolidines from Aroylformates and δ-Tosylamino Enones via P(NMe2)3-Mediated Reductive Amination/Base-Catalyzed Michael Addition Cascade" Org. Lett. 2020, 22, 6922-6926. (IF: 6.555)

[5]Zhou, R.*; Ma, L.*; Yang, X.; Cao, J. "Recent advances on visible-light photocatalytic deuteration reactions" Org. Chem. Front. 2020, DOI: 10.1039/D0QO01299H. (IF: 5.155)

[6]Gao, W.-C.*; Shang, Y.; Chang, H.-H.; Li, X.; Wei, W.-L.; Yu, X.; Zhou, R.* “N-Alkynylthio Phthalimide: A Shelf-stable Alkynylthio Transfer Reagent for the Synthesis of Alkynyl Thioethers” Org. Lett. 2019, 21, 6021-6024. (IF: 6.555)

[7]Zhou, R.*; Liu, R.; Zhang, K.; Han, L.; Zhang, H.; Gao, W.*; Li, R. “Metal-Free Formal Carbon-Halogen Bond Insertion: Facile Syntheses of 3-Halo 3,3'-Disubstitutedoxindoles and Spirooxindole-g-butyrolactones” Chem. Commun. 2017, 53, 6860-6863. (IF: 6.164)

[8]Zhou, R.*; Zhang, K.; Chen, Y.; Meng, Q.; Liu, Y.; Li, R.; He, Z.* “P(NMe2)3-mediated reductive [1 + 4] annulation of isatins with enones: a facile synthesis of spirooxindole-dihydrofurans” Chem. Commun. 2015, 51, 14663-14666. (IF: 6.164)

[9]Zhou, R.; Wang, J.; Duan, C.; He, Z.* “Phosphine-Triggered Tandem Annulation between Morita-Baylis-Hillman Carbonates and Dinucleophiles: Facile Syntheses of Oxazepanes, Thiazepanes, and Diazepanes” Org. Lett. 2012, 14, 6134-6137. (IF: 6.555)

[10]Zhou, R.; Wang, J.; Song, H.; He, Z.* “Phosphine-Catalyzed Cascade [3 + 2] Cyclization-Allylic Alkylation, [2 + 2 + 1] Annulation, and [3 + 2] Cyclization Reactions between Allylic Carbonates and Enones” Org. Lett. 2011, 13, 580-583. (IF: 6.555)

[11]Zhou, R.; Wang, C.; Song, H.; He, Z.* “Wittig Olefination between Phosphine, Aldehyde, and Allylic Carbonate: A General Method for Stereoselective Synthesis of Trisubstituted 1,3-Dienes with Highly Variable Substituents” Org. Lett. 2010, 12, 976-979. (Highlighted in Organic Chemistry Portal) (IF: 6.555)

[12]Zhou, R.*; Han, L.; Zhang, H.; Liu, R.*.; Li, R. “A Deoxygenative [4 + 1] Annulation Involving N-Acyldiazenes for Efficient Synthesis of 2,2,5-Trisubstituted 1,3,4-Oxadiazole Derivatives” Adv. Synth. Cat. 2017, 359, 3977-3982. (IF: 5.451)

[13]Zhou, R.*; Zhang, K.; Han, L.; Chen, Y.; Li, R.; He, Z. "Unusual Formal [1+4] Annulation through Tandem P(NMe2)3-Mediated Cyclopropanation/Base-Catalyzed Cyclopropane Rearrangement: Facile Syntheses of Cyclopentenimines and Cyclopentenones" Chem. Eur. J. 2016, 22, 5883-5887. (IF: 5.160)

[14]Zhou, R.*; Yang, C.; Liu, Y.; Li, R.; He, Z.* “Diastereoselective Synthesis of Functionalized Spirocyclopropyl Oxindoles via P(NMe2)3‑Mediated Reductive Cyclopropanation” J. Org. Chem. 2014, 79, 10709-10715. (IF: 4.745)

[15]Zhou, R.; Wang, J.; Yu, J.; He, Z.* “Highly Chemoselective Rauhut−Currier Reaction between Maleimides and Enones and Dual Phosphine-Mediated One-Pot Synthesis of Bicyclic and Polycyclic Skeletons” J. Org. Chem. 2013, 78, 10596-10604. (IF: 4.745)

[16]Zhou, R.; Duan, C.; Yang, C.; He, Z.* “Phosphane-Catalyzed [4+1] Annulation between Nitroalkenes and Morita–Baylis–Hillman Carbonates: Facile Synthesis of Isoxazoline N-Oxides by Phosphorus Ylides” Chem. Asian J. 2014, 9, 1183-1189. (IF: 3.698)

[17]Gao, W.-C.,* Liu, T., Cheng, Y.-F., Chang, H.-H., Li, X., Zhou, R.*, Wei, W.-L., Qiao, Y. “AlCl3-Catalyzed Intramolecular Cyclization of N-Arylpropynamides with N-Sulfanylsuccinimides: Divergent Synthesis of 3-Sulfenyl Quinolin-2-ones and Azaspiro[4,5]trienones” J. Org. Chem. 2017, 82, 13459-13467. (IF: 4.745)

[18]Liu, R.; Qin, Z.; Fan, B.; Li, R.; Zhou, R.*; He, Z.* "Phosphine-Catalyzed Chemo- and Diastereoselective [2 + 2 + 2] and [3 + 2] Annulations of γ-Methyl Allenoates with Doubly Activated Olefins: Syntheses of Highly Substituted Cyclohexanes and Cyclopentenes" J. Org. Chem. 2019, 84, 12490-12498. (IF: 4.745)

[19]Zhou, R.*; Zhang, H.; Liu, J.; Liu, R.; Gao, W.-C.*; Qiao, Y.; Li, R. “Chemoselective P(NMe2)3-Mediated Reductive Epoxidation between Two Different Carbonyl Electrophiles: Synthesis of Highly Functionalized Unsymmetrical Epoxides” J. Org. Chem. 2018, 83, 8272-8280. (IF: 4.745)

[20]Gao, W.-C.*; Cheng, Y.-F.; Shang, Y.-Z.; Chang, H.-H.; Li, X.; Zhou, R.*; Qiao, Y.; Wei, W.-L. "Copper(II)-Catalyzed Four-Component Oxysulfonylation/Diazenylation: Synthesis of α‑Arylhydrazo-β-keto Sulfones" J. Org. Chem. 2018, 83, 11956-11962. (IF: 4.745)

[21]Zhou, R.; Wang, J.; Tian, J.; He, Z.* “Phosphine-catalyzed [4 + 2] annulation and vinylogous addition reactions between 1,4-dien-3-ones and 1,1-dicyanoalkenes” Org. Biomol. Chem. 2012, 10, 773-781. (IF: 3.490)

[22]Yang, C.; Li, J.; Zhou, R.*; Chen, X.; Gao, Y.; He, Z.* “Facile synthesis of spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines and their fungicidal activity” Org. Biomol. Chem. 2015, 13, 4869-4878. (Cover Article) (IF: 3.490）

[23]Zhou, R.*; He, Z." Advances in Annulation Reactions Initiated by Phosphorus Ylides Generated in situ" Eur. J. Org. Chem. 2016, 1937-1954. (IF: 3.029)

[24]Liu, J.; Cao, J.; Liu, R.; Li, R.; Qiao, Y.; Zhou, R.* "Condensation of 1,2-Dicarbonyl Compounds with Modified Huisgen Zwitterions: Synthesis of N-Aryl-N-Acyl Hydrazones" Org. Biomol. Chem. 2020, 18，530-537. (IF: 3.490)

[25]Liu, R.; Chia, S. P. M.; Goh, Y. Y.; Cheo, H. W.; Fan, B.; Li, R.; Zhou, R.*; Wu, J.* “Visible-Light-Mediated Regioselective Allylation, Benzylation, and Silylation of Methylene-Malononitriles via Photoredox-Induced Radical Cation Fragmentation” Eur. J. Org. Chem. 2020, 1459-1465. (IF: 3.029)

[26]Zhang, H.; Zhou, R.* "Recent Advances in Phosphine-Promoted (4+1) Annulation Reactions" 2020, 4098-4107.

[27]Zhang, H.; Liu, R.; Liu, J.; Fan, B.; Li, R.; Qiao, Y.; Zhou, R.* "Chemoselective Phosphine-Catalyzed Cyanoacylation of α-Dicarbonyl Compounds: A General Method for Synthesis of Cyanohydrin Esters with One Quaternary Stereocenter" New. J. Chem. 2018, 42, 19720-19728. (IF: 3.069)

[28]Qin, Z.; Liu, R.; Zhou, R.*; Li, R.; He, Z.* "Phosphine-Catalyzed [3 + 2] and [2 + 4] Annulations of γ-Methyl Allenoates with Aryl α-Keto Esters: Stereoselective Syntheses of Functionalized Tetrahydrofurans and 4-Chromanols" Asian J. Org. Chem. 2020, 9, 86-93. (IF: 2.496)

[29]Liu, Y.*; Zhou, R.* “Progress in Annulation Reactions Based on Huisgen Zwitterion” Chin. J. Org. Chem. 2019, 39, 2365-2378.

[30]Zhou, R.*; Liu, R.; Li, R.; He, Z.* “Progress in Phosphine-Promoted Annulations between Two Electrophiles” Chin. J. Org. Chem. 2014, 34, 2385-2405. (Cover Article) .

[31]Liu, R.; Han, L.; Liu, J.; Fan, B.; Li, R.*; Qiao, Y.; Zhou, R.* "Facile synthesis of 2,3-disubstituted benzofurans via DBU-promoted intramolecular annulation of ortho oxyether aroylformates" Synth. Commun. 2018, 48, 3079-3088.

[32]Zhou, R.*, Zhang, K., Rongfang Liu “Facile Synthesis of Bisphosphine Monoxides from Morita-Baylis-Hillman Carbonates” Phosphorus Sulfur and Silicon Relat. Elem. 2016, 191, 885-890.

[33]Tian J.; Zhou, R.; Sun, H.; Song, H.; He, Z.* “Phosphine-Catalyzed [4 + 1] Annulation between a,β-Unsaturated Imines and Allylic Carbonates: Synthesis of 2-Pyrrolines” J. Org. Chem. 2011, 76, 2374-2378.

[34]Wang, J.; Zhou, R.; He, Z.-R.; He, Z.* “Phosphane-Mediated Domino Synthesis of Tetrasubstituted Furans from Simple Terminal Activated Olefins” Eur. J. Org. Chem. 2012, 30, 6033-6041.

[35]Tian, J.; Sun, H.; Zhou, R.; He, Z.* “Phosphine-Catalyzed Annulations between Modified Allylic Derivatives and Polar Dienes and Substituent Effect on the Annulation Mode” Chin. J. Chem. 2013, 31, 1348-1351.

[36]Liu, H.; Ma, L.; Zhou, R.; Chen, X.; Fang, W.; Wu, J. "One-Pot Photomediated Giese Reaction/Friedel−Crafts Hydroxyalkylation/Oxidative Aromatization To Access Naphthalene Derivatives from Toluenes and Enones" ACS Catal. 2018, 8, 6224-6229.